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UKZN PhD explores medicinal potential of invasive bugweed

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By Lebone Rodah Mosima

Dr Myuri Parusnath has earned a PhD in Biology from the University of KwaZulu-Natal for research into plant-based bioactive compounds in Solanum mauritianum, commonly known as bugweed.

Her study, titled “Secretory, Phytochemical and Biological Activities of Solanum mauritianum Scop. (Solanaceae),” examined the chemical and biological properties of the plant, which is classified as an invasive species in South Africa.

Parusnath said plants that thrive across diverse environments often develop complex chemical defence systems, some of which may have medicinal value.

“In this study, I investigated the microscopic structures of the plant, analysed its chemical composition and evaluated several biological activities, including antioxidant, antibacterial and cytotoxic properties,” Parusnath said.

“The aim was to explore whether this plant could serve as a potential source of natural bioactive compounds.”

She said the research was particularly relevant given the growing problem of antibiotic resistance and the need to explore alternative therapeutic options.

“In many parts of the world, medicinal plants remain an important component of healthcare, and scientific studies such as this help validate and expand our understanding of their potential applications,” she said.

Parusnath’s interest in the field was rooted in a longstanding curiosity about science and the natural world.

“Always fascinated by how biological systems function and how research can uncover new insights, the possibility of exploring plants as sources of biologically active compounds and contributing to discoveries that might one day support therapeutic development strongly motivated her work,” UKZN said.

The research adds to the growing body of knowledge about plant-derived compounds and their potential value.

“By examining the chemical composition and biological activity of Solanum mauritianum, my research helps build a scientific foundation that future studies can expand upon, particularly in the search for plant-based therapeutic agents,” Parusnath said.

Parusnath remains actively involved in academic life and student development.

She serves as a First-Year Experience Coordinator in the College of Agriculture, Engineering and Science and works as a part-time lecturer in Biology in the School of Agriculture and Science.

“Long-term she aspires to build a career in academia and research while mentoring and supporting future generations of students,” UKZN said.

“Parusnath credited several people who helped her reach this milestone including her supervisor, Professor Yougasphree Naidoo, and co-supervisor, Professor Moganavelli Singh, who mentored and guided both her master’s and doctoral studies.”

Parusnath also expressed gratitude to her parents, brother and friends for their support during her studies.

She emphasised the importance of maintaining balance. In her spare time, she enjoys going to the gym, exploring creative interests such as makeup, and spending time with friends and family.

Reflecting on the broader significance of her achievement, Parusnath said she hoped her journey would inspire others, particularly young women considering careers in science.

“Doctoral graduates represent a small proportion of the global population, and women remain underrepresented in many scientific fields,” she said.

“Through my work and example, I hope to encourage more women to pursue paths in science, research and higher education.”

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